Author : Vossen, J.M.B.M..; Havekes, W.A.L.M.; Koster, D.S.; Ten Brink, B.; Minekus, M.; Havenaar, R.; Huis in't Veld, J.H.J.

Summary : Conclusions: The gastrointestinal tract models were shown useful for a comparative study of digestibility and availability of nutrients of modified and non-modified tomatoes. Significant differences in the availability of nutrients related to the input of modified or control tomatoes were not observed. In addition, no differences were observed in the nutrients that were delivered at the end of the ileal compartment. This material did not influence the activity and composition of the micro flora in the colon compared to feeding of the colon with normal colon medium. The gastrointestinal tract model is highly suitable for pre-screening studies for the evaluation of the safety of novel foods. However, in order to show the value of the model, examples are needed in which the modified and non-modified food are highly different.