Summary : Because caffeine is so widely consumed, the FDA and medical researchers have conducted extensive research and have carefully reviewed caffeine's safety, even since caffeine was placed on the US FDA's Generally Recognized as Safe (GRAS) list in 1958. In 1978, the agency recommended additional research be conducted to resolve any uncertainties about its safety. In 1987, FDA reaffirmed its position that scientific evidence does not indicate caffeine in carbonated beverages creates any adverse effects in humans. Furthermore, both the National Academy of Sciences National Research Council and the US Surgeon General's office report there has been no association established between caffeine, as normally consumed in our diet, and an increased risk to health.