Bt maize is a proven safe and effective technology that has the potential to deliver benefits on 25 million hectares through hybrid systems in temperate mega-environments, amongst which China offers the most important opportunity. In the tropical environments with a potential of 18 million hectares of Bt maize through hybrid systems, the most important opportunity is in Brazil. Bt maize offers a unique opportunity and an incentive for major maize consuming, developing countries to approve and adopt Bt maize and benefit from the multiple and significant benefits it offers in terms of a safer and more affordable food and feed, which can coincidentally make a major contribution to food and feed security and to the alleviation of hunger and malnutrition which claims 24,000 lives a day in the developing countries of Asia, Africa and Latin America.