Author : Ratna Asmah Susidarti

Summary : Extraction and separation of the leaves and stem bark of E. chloranta yielded friedelin (43) which possessed moderate cytotoxic activity (IC50 of 5.8 µg/ml). The essential oil of leaves of this plant constituted principally oxygenated sesquiterpenes and showed weak cytotoxic and antibacteria activities. The methanol and aqueous extracts of the leaves possessed antiinflammatory activity, but they performed relatively lower activity than indomethacin. From the stem bark of E. cumingiana, beta-sitosterol (41) and two unidentified compounds were isolated. In addition, all the extracts, essential oil and isolated compounds from the plants studied were inactive towards the target fungi.